Knee Replacement Scheduled?Join This Paid Virtual Research Study
✅ Earn up to $50 in compensation
Recovering from knee replacement isn't just about healing your knee—it's about supporting your whole body and mind.
Researchers at the University of Arizona are studying whether brief at-home activities after surgery can help them better understand stress and recovery following total knee replacement.
Participation is 100% virtual and includes short activities, online surveys and at-home saliva samples on post-operative days 2 and 3. All study materials and instructions are provided, and your usual medical care will not change.
If you're 65 or older and scheduled for an elective total knee replacement within the next 5 days to 2 months, you may qualify. Participants can earn up to $50 in compensation for completing study activities.
Why Participate?
Try a simple virtual activity after your knee replacement, at no cost and alongside your usual care.
Earn up to $50 in compensation for completing study activities.
Support your recovery with short daily exercises and surveys - results may vary.
Help researchers learn how these activities could benefit future knee replacement patients.
Eligibility Requirements
Who Cannot Participate
Who Can Participate
Currently using steroid (corticosteroid) medications in any form (pills, injections, inhalers, nasal sprays, or creams)
Lack access to a smartphone, tablet, or computer with reliable internet
Has any of the following conditions:
Conditions that affect cortisol or steroid hormone levels (such as Cushing’s syndrome, Addison’s disease, or pituitary/adrenal gland tumors)
Asthma
Severe mental health or cognitive conditions that require a legal decision-maker (Durable Power of Attorney)
Chronic obstructive pulmonary disorder
Heart failure
Complete heart block that requires a pacemaker
Glaucoma
Epilepsy
Asthma
Be scheduled for an elective total knee replacement (TKA) in 5 days to 2 months (second knee is okay; revision surgeries are not eligible).
Be generally healthy, without serious conditions that make deep breathing unsafe or uncomfortable
Be able to read and understand English and follow emailed instructions
Be able to virtually attend study visits and participate in the required study procedures
Study Process
The study team will explain the research in its entirety, but some details include:
Participants will be asked to check their email daily after consenting and follow emailed instructions, including completing brief surveys and study tasks from the day of surgery through post-op day 3. They must be able and willing to check their mailbox for saliva sample testing kits.
Participants will be asked to collect saliva samples at home using mailed kits, three times a day for two days after surgery (post-op days 2 and 3).
Participants will be asked to complete a short 5-minute activities three times a day for two days, and finish final surveys on post-op day 3.
Participants should be willing to stay in contact with the study team by phone, text, or email and respond to study communications during the study period.
Eligibility will be confirmed before consent and again after surgery to ensure participant safety and study requirements are met.
Meet the Lead Researcher
Devon Cobos Garcia, PhD Candidate, MS, BSN, RN
Devon E. Cobos Garcia is a Nursing PhD Candidate and Post-Anesthesia Care Unit Registered Nurse. She has been a Registered Nurse for almost nine years, with most of her nursing career spent helping patients prepare for and recover from surgery, including total knee replacements. She is earning her PhD from the University of Arizona, has a BS in Nursing and a BS in Psychology from the University of North Florida, and an MS in Psychology from Florida International University.
Study Location
This is a virtual study in the United States
As the #1 nursing college in Arizona, the College of Nursing is a renowned institution dedicated to excellence in nursing education, research, and practice. Our goal is to prepare the next generation of compassionate and highly skilled nurses who will positively impact healthcare outcomes and enhance the well-being of individuals, families, and communities.
Your Safety Comes First
Ethics Approved Research Studies
This study has been reviewed and approved by the University of Arizona IRB
Qualified Study Professionals
Qualified health professionals will monitor your health as it relates to the study.
Ethical Recruitment Practices
The Trialfacts team is GCP-trained, ensuring the rights, safety, and well-being of research subjects are protected.
Privacy Standards You Can Trust
We adhere to all national privacy standards used by doctors’ offices, hospitals, and medical institutions.
Your Safety Comes First
This study has been reviewed and approved by the University of Arizona IRB
Ethics Approved Research Studies
Qualified health professionals will monitor your health as it relates to the study.
Qualified Study Professionals
The Trialfacts team is GCP-trained, ensuring the rights, safety, and well-being of research subjects are protected.
Ethical Recruitment Practices
We adhere to all national privacy standards used by doctors’ offices, hospitals, and medical institutions.
Privacy Standards You Can Trust
Participant’s Rights
Informed Consent
You will receive a detailed outline of all details of the study, including risks and procedures, and you will be given the chance to ask study staff questions before you decide whether to participate.
Withdraw At Any Time
If you decide to participate in the study and later feel that you no longer wish to be part of it, you can withdraw at any time
Secure and Confidential Data
Your records relating to this study and any other information received will be kept strictly confidential, except as required by law.
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