Could oral health reveal risks for Alzheimer’s disease? Emory University researchers are studying the link between gum health, the oral microbiome, and Alzheimer’s risk in middle-aged to older adults. 

The goal is to identify pathways that could enable early screening and prevention. This study could help individuals at risk receive care sooner and improve overall health outcomes.

Interested? See if you qualify for this study!

• Men and women aged 45 - 85 who have at least 16 natural teeth
• Must not have a history of endocarditis, previous valve replacement or heart disease
• Must not have current oral cancers or systemic inflammatory conditions (eg. Rheumatoid arthritis, IBD, SLE)
• Must be able to attend 3 study visits at the research site over 1 year

• Participants will be compensated up to $375 for participating in this study. Compensation will only be provided to eligible participants who complete the study.
• Participants will provide valuable insights into the link between gum disease, the oral microbiome, and Alzheimer’s risk factors.
• Participants will be helping to advance medical research.

• Participants will be asked to answer questionnaires.
• Participants will be asked to provide blood collected by a trained phlebotomist and cerebrospinal fluid through a lumbar puncture collected by a licensed neurologist.
• Participants will be asked to have a dentist examine their gum health and collect oral specimens, such as saliva and plaque.

Irene Yang, PhD, RN

Research Site:

Emory University

Location:

1520 Clifton Road, NE, Atlanta, GA 30322

Lead Researcher:

Irene Yang, PhD, RN

Ethics Committee:

This study has been reviewed and approved by the Emory University Institutional Review Board

This trial has been reviewed and approved by an independent ethics committee. 

All research staff that are running this trial have been trained in GCP, which assures that the rights, safety, and well-being of research subjects are protected and respected.

Qualified health professionals will monitor your health as it relates to the study.

All data you provide us is encrypted and stored safely and securely in accordance with security and privacy rules.

We follow all established national privacy standards used in all doctors' offices, hospitals and other businesses where personal medical information is stored.

Informed Consent Before Participation

Withdraw At Any Time

Strictly Confidential

You will receive a detailed outline of all details of the study, including treatment, risks and procedures, and given the chance to ask questions to study staff, before you decide whether to participate.

If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.

Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.

Informed Consent Before Participation

Withdraw At Any Time

Strictly Confidential

Your records relating to this study and any other information received will be kept strictly confidential, except as required by the law.

If you decide to participate in the study and later feel that you no longer wish to be part of it, you may withdraw at any time.

You will receive a detailed outline of all details of the study, including treatment, risks and procedures, and given the chance to ask questions to study staff, before you decide whether to participate.

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